normalise_junc: Normalise junction counts for RNA-seq samples

In dzhang32/RNAdiagnosR: What the Package Does (One Line, Title Case)

Description

normalise_junc takes as input the junction co-ordinates and counts for samples and normalises the counts for each sample using total number of counts for junctions that share an start or end with that junction

Usage

normalise_junc(junc_coords, raw_counts, use_strand = T)

Arguments

junc_coords	gr. Junction co-ordinates in a GRanges format
raw_counts	df. Detailing the counts for each junction for all samples. Each column is a sample and each row corresponding to a junction.
use_strand	lgl scalar. Whether to use the strand information when clustering junctions.

Value

list. Raw and normalised counts including metdata detailing co-ordinates and clusters.

dzhang32/RNAdiagnosR documentation built on Dec. 5, 2019, 2 a.m.