edpratt1/KINATESTID: A Pipeline for Kinase-Specific Artificial Peptide Design

This pipeline employs a combination of curated collections of known endogenous substrate sequences and data from phosphoproteomics- informed kinase assays to develop an in silico peptide library. This library is used for systematic identification of position-specific amino acid preferences. These preferences inform the design of artificial candidate sequences optimized for kinase-specific performance which can then be characterized in vitro or in vivo.

Getting started

Package details

AuthorErica D. Pratt [aut, cre], John B. Blankenhorn [aut], Laurie L. Parker [aut]
MaintainerErica D. Pratt <epratt@bu.edu>
License
Version2.1.1
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("edpratt1/KINATESTID")
edpratt1/KINATESTID documentation built on Feb. 5, 2022, 1:21 p.m.