This pipeline employs a combination of curated collections of known endogenous substrate sequences and data from phosphoproteomics- informed kinase assays to develop an in silico peptide library. This library is used for systematic identification of position-specific amino acid preferences. These preferences inform the design of artificial candidate sequences optimized for kinase-specific performance which can then be characterized in vitro or in vivo.
Package details |
|
---|---|
Author | Erica D. Pratt [aut, cre], John B. Blankenhorn [aut], Laurie L. Parker [aut] |
Maintainer | Erica D. Pratt <epratt@bu.edu> |
License | |
Version | 2.1.1 |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
|
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.