Description Usage Arguments Value
Calculates Q-matrix for bivariate profile likelihoods for BiChroM model
1 | Q_bibichrom(log.pars, log.theta0, size, param.name)
|
log.pars |
vector of size 8 indicating values in ln of nuisance parameters (excluding the ones of interest for the profile likelihood) |
log.theta0 |
vector of size 2 indicating values parameters of interest in BiChroM. Options are (lambda0, lambda1, mu0, mu1, rho0, rho1, q01,q10, e01, e10) |
size |
Maximum number of chromosomes in the sample (recommended no more than 50, states larger than that should be coded as 51) |
param.name |
vector of size 2 indicating the names of parameters of interest. E.g. c("rho0","rho1") |
Q a sparse matrix of size 2*(size+1)
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