get_fva_intervals_from_observations: Get intervals of flux variability (FVA) from an observed...

Description Usage Arguments Value Examples

Description

Get intervals of flux variability (FVA) from an observed growth rate

Usage

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get_fva_intervals_from_observations(model, observed_growth_rate,
  metabolites_rates = NULL,
  biomass_flux_index = get_biomass_flux_position(model))

Arguments

model

a genome-scale metabolic model of class modelorg

observed_growth_rate

a numerical value for the observed growth rate

metabolites_rates

Optional. a data.frame consisting of the name of the metabolites, their concentrations and rates in mmol/gDW/h to adjust the model uptake rates. The column name must be "name", "concentrations","rates"

biomass_flux_index

Optional. Index of the biomass flux as returned by get_biomass_flux_position()

Value

Return the interval of fluxes values compatible with the observed growth rate through flux variability analysis

Examples

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data("iMM904")
metabolites_rates<-data.frame(name=c("D-Glucose","Glycerol"),
                         concentrations=c(16,0),rates=c(-2.81,-8.01))

FluxesVarFromObs<-get_fva_intervals_from_observations(iMM904,0.205,
metabolites_rates=metabolites_rates)

i3bionet/CoRegFlux documentation built on May 31, 2019, 1:50 a.m.