Description Usage Arguments Value
This function parses interactions from a single experiment by a given resolution. It takes a path to a directory with uncompressed raw data and subdirectories for each cell-type. The data can be manually downloaded and from this url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63525.
1 2 | parseRaoHiCtoGI(cell, resolution, baseDir, seqInfo, interChromosomal = TRUE,
normalizeByExpected = FALSE, mapQual = "MAPQGE30", norm = NULL)
|
cell |
The cell type of the input experiment |
resolution |
The matrix resolution of the Hi-C map in bp |
baseDir |
The path to the directory with the Hi-C data. |
seqInfo |
A seqinfo object of the genome. |
interChromosomal |
logical idicating whether inter-chromosomal contacts should be parsed. |
normalizeByExpected |
Should contact frequencies be normalized by distance. Default is FALSE. |
mapQual |
character representing the mapping quality threshold. Defualt is "MAPQGE30". |
norm |
character representation of the normalization method to use. Default is NULL meaning that no normalization is applied. Possible values are "KR" or "VC". This is not impplemented yet. |
GInteractions
object with all cis- and
trans-interactions
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