Johansson_residuals: Johansson HM450K methylation data

Description Usage Format Details Source References

Description

Methylation values based on the data set obtained by Johansson et al. \insertCitejohansson2013continuousmeNet. Methylation beta values for 728 healthy samples were obtained with Illumina HM450K microarray. In the step of data preparation and preprocessing, problematic CpGs were removed and the original beta values were adjusted for age, sex and cell counts. 'meNet::Johansson_residuals' data frame contains the residuals of the preprocessing analysis for chromosome 21.

Usage

1

Format

A data frame with 3536 rows and 728 columns. Row names are unique CpG identifiers from the Illumina CG database.

Details

Some CpG sites from chromosome 21 are not included. They may be omitted in the original data set or removed during the preprocessing. Moreover, CpG sites are the same as in the 'meNet::Bacalini_betaValues' data set and thus only the intersection of measured CpGs remains.

Source

Original data set was downloaded from the Gene Expression Omnibus (GEO) data repository as a data set with accession number GSE87571 https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE87571.

References

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ivabudimir/meNet documentation built on Dec. 20, 2021, 8:03 p.m.