jasonratcliff/aggregateBioVar: Differential Gene Expression Analysis for Multi-subject scRNA-seq

For single cell RNA-seq data collected from more than one subject (e.g. biological sample or technical replicates), this package contains tools to summarize single cell gene expression profiles at the level of subject. A SingleCellExperiment object is taken as input and converted to a list of SummarizedExperiment objects, where each list element corresponds to an assigned cell type. The SummarizedExperiment objects contain aggregate gene-by-subject count matrices and inter-subject column metadata for individual subjects that can be processed using downstream bulk RNA-seq tools.

Getting started

Package details

Bioconductor views DifferentialExpression GeneExpression RNASeq SingleCell Software Transcription Transcriptomics
URL https://github.com/jasonratcliff/aggregateBioVar
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
jasonratcliff/aggregateBioVar documentation built on Sept. 29, 2020, 11:53 p.m.