convert_units: Convert pmol/min/ug_protein or pmol/min/ug_DNA to...

In jdreyf/sybilxf: R package for integration of Seahorse extracellular flux (XF) data with metabolic modeling.

Description

This function takes the matrix returned by sample_seahorse and multiplies it by a factor

Usage

convert_units(x, mwr = 0.706)

Arguments

x	A matrix
mwr	Macromolecular weight ratio

Details

The macromolecular weight ratio is the relationship between the initial normalization (typically DNA or protein) and total dry weight. It can vary substantially depending on cell type. By default, mwr = 0.706, which is the estimated protein/dry_weight ratio from the biomass reaction in Recon 2. For adipocytes, mwr = 0.026

Author(s)

Alfred Ramirez

References

Ramirez AK, Lynes MD, Shamsi F, Xue R, Tseng YH, Kahn CR, Kasif S, Dreyfuss JM. Integrating Extracellular Flux Measurements and Genome-Scale Modeling Reveals Differences between Brown and White Adipocytes. Cell Rep 2017 Dec; 21(11): 3040-3048.

jdreyf/sybilxf documentation built on May 22, 2019, 4:41 p.m.