gen.CompMatrix: Generate a comparison matrix

In jwinget/mrmr: Functions to improve MRM data processing with MSstats

Description

Given a matrix of desired comparisons and original group levels, generate the comparison matrix for MSstats

Usage

gen.CompMatrix(mat, lev)

Arguments

mat	A matrix with desired condition comparisons, 2 or 4 columns
lev	Condition levels from the processed data

Value

An MSstats comparison matrix

Examples

# Set up a matrix with desired comparisons
# For a double difference, the conditions in positions 1 & 4 will be set to 1
# and conditions in positions 2 & 3 will be set to -1, so these are like
# (Trt.Trted - Trt.Baseline) - (Veh.Trted -  Veh.Baseline)

el <- matrix(c('B.3','B.1','A.3','A.1',
               'B.4','B.1','A.4','A.1',
               'C.3','C.1','A.3','A.1',
               'C.4','C.1','A.4','A.1',
               'C.3','C.1','B.3','B.1',
               'C.4','C.1','B.4','B.1',
               'D.3','D.1','E.3','E.1',
               'D.4','D.1','E.4','E.1',
               'Y.3','Y.1','Z.3','Z.1',
               'Y.4','Y.1','Z.4','Z.1'),
             ncol=4, byrow = T)

orig.levels <- levels(rd.proposed$ProcessedData$GROUP_ORIGINAL)

# Generate MSstats comparison matrix from the graph and original groups
comparisons <- gen.CompMatrix(el, orig.levels)

jwinget/mrmr documentation built on Nov. 4, 2019, 3:28 p.m.