extendTranscriptsPerGene: Extend truncated transcripts to the longest annotated...

Description Usage Arguments Value Author(s)

Description

Identify transcripts that are flagged as start or end not found and extend them by adding missing exons from the longest transcript of the gene. Importantly, if the last exon at the truncated end is not present in the longest transcript, then the truncated transcript will not be extended, because there is no information supporting that exon junction.

Usage

1
extendTranscriptsPerGene(metadata, exons, cdss)

Arguments

metadata

data frame of transcript metadata (required columns: ensembl_transcript_id, longest_start, longest_end, cds_start_NF, cds_end_NF, cds_start_end_NF).

exons

named list of GRanges objects containing the exon coordinates for each transcript.

cdss

named list of GRanges objects containing the CDS coordinates for each transcript.

Value

List of GRanges lists (exons and cdss). Contains the update exon and CDS coordinates for transcripts that were previously truncated.

Author(s)

Kaur Alasoo


kauralasoo/reviseAnnotations documentation built on May 20, 2019, 7:41 a.m.