malley1: Effect of immunization on the pneumococci infection in mice

In kbroman/labstat: Statistics for Lab Scientists

Description

Number of mice colonized by pneumococci when challenged 2 weeks post-immunization, with several different immunogens (including a control), all without adjuvant.

Usage

data(malley1)

Format

A data frame with two columns: number colonized and total number.

References

Malley, R., Lipsitch, M., Stack, A., Saladino, R., Fleisher, G., Pelton, S., Thompson, C., Briles, D. and Anderson, P. (2001) Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococci. Infection and Immunity 69:4870–4873. (See Table 1.)

See Also

malley2, malley3

Examples

data(malley1)
# p-values by Fisher's exact tests
p <- 1:4
for(i in 1:4) {
  x <- malley1[c(1,i+1),]
  x[,2] <- x[,2]-x[,1]
  p[i] <- fisher.test(x)$p.value
}
round(p,3)

kbroman/labstat documentation built on Jan. 6, 2021, 4:51 a.m.