malley3: Effect of immunization on the pneumococci infection in rats

In kbroman/labstat: Statistics for Lab Scientists

Description

Number of rats colonized by pneumococci post-immunization, with adjuvant alone versus adjuvant and killed Rx1AL- immunogen.

Usage

data(malley3)

Format

A data frame with four columns: replicate (A/B), number of ill rats, number of dead rats, and total number of rats.

References

Malley, R., Lipsitch, M., Stack, A., Saladino, R., Fleisher, G., Pelton, S., Thompson, C., Briles, D. and Anderson, P. (2001) Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococci. Infection and Immunity 69:4870–4873. (See Table 2.)

See Also

malley1, malley2

Examples

data(malley3)
# p-values by Fisher's exact tests
p <- 1:4
# repl A; ill
x <- malley3[1:2,c(2,4)]
x[,2] <- x[,2]-x[,1]
p[1] <- fisher.test(x)$p.value
# repl A; dead
x <- malley3[1:2,c(3,4)]
x[,2] <- x[,2]-x[,1]
p[2] <- fisher.test(x)$p.value
# repl B; ill
x <- malley3[3:4,c(2,4)]
x[,2] <- x[,2]-x[,1]
p[3] <- fisher.test(x)$p.value
# repl B; dead
x <- malley3[3:4,c(3,4)]
x[,2] <- x[,2]-x[,1]
p[4] <- fisher.test(x)$p.value

kbroman/labstat documentation built on Jan. 6, 2021, 4:51 a.m.