berrios: Cell surface adhesion receptor expression

Description Usage Format Source References See Also Examples

Description

Data on cell surface adhesion receptor expression in ATII cells (from rats) after 1, 4 and 7 days of culture.

Usage

1

Format

A data frame with three columns: days in culture, receptor molecule, and light intensity (a correlate of receptor expression).

Source

Rolf D. Hubmayr, Mayo Clinic and Foundation, Rochester, MN

References

Berrios, J. C., Schroeder, M. A. and Hubmayr, R. D. (2001) Mechanical properties of alveolar epithelial cells in culture. J. Appl. Physiol. 91, 65–73. (See Figure 2.)

See Also

sem

Examples

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data(berrios)

# means and SEs
me <- tapply(berrios[,3], list(berrios[,2], berrios[,1]), mean, na.rm=TRUE)
se <- tapply(berrios[,3], list(berrios[,2], berrios[,1]), sem)
se <- se/me[,1]*100
me <- me/me[,1]*100
me <- as.numeric(t(me))[-6]
se <- as.numeric(t(se))[-6]

# barplot
par(las=1)
barplot(me, col=c("white","gray80","gray40","white","gray80"),
        names.arg=as.character(c(1,4,7,1,4)),
        ylim=c(0,250),xlim=c(0,5.5),width=1,space=c(0,0,0,0.5,0),
        ylab="Relative Light Intensity",xlab="Day")
abline(h=0)
x <- c(0.5,1.5,2.5,4,5)
segments(x,me,x,me+se,lwd=2)
segments(x-0.1,me+se,x+0.1,me+se,lwd=2)
text(1.5,225,"ICAM-1",cex=1.3,font=2)
text(4.5,225,"RGD-Peptide",cex=1.3,font=2)

kbroman/labstat documentation built on Jan. 6, 2021, 4:51 a.m.