calculate.bij | Calculate the background mutation probability for every... |
calculate.post.probs | Calculate posterior probability of being a driver |
compRatio | Cubic spline logistic regression |
convert.hgnc.to.ensembl | Convert HGNC symbols to Ensembl identifiers using biomaRt |
convert.seq.to.num | Convert nucleotide sequence to numbers |
dCG.type | Get mutation type (5-6) of CpG mutations |
exome | Exome annotation for human genome build NCBI 36/hg18 |
find.prior.param | Find the maximum likelihood values for the hyperparameters... |
fit.background.model | Fit background mutation model |
gene_names | Ensembl names for all genes in the exome |
generate.sel.exome | Select the part of exome.constants that belongs to a list of... |
gene.rep.expr | Gene annotation list |
getA | Compute A - the likelihood of a mutation at every position |
get.post.probs | Main posterior probability calculation |
locfdr | Estimation of non-null density |
lupost2.vec | Likelihood of sample specific mutation rate given the... |
lupost3.vec | Likelihood of sample specific mutation rate given the... |
lupost4.vec | Posterior mean of sample-specific mutation rate given the... |
lupost.vec | Likelihood of mutations in a single gene and sample given the... |
multiply.p.s.epsilon | Multiply the constants in 'exome.constants' by the relative... |
multiplyr | Multiply the nonsilent constants in a subsetted... |
mut.base | Convert nucleotide sequence to column numbers in 'exome.SIFT' |
mut.lik.change | Calculate change in likelihood due to background mutations |
mut.type | Get mutation type (transition or transversion) |
mut.type.converter | Get total counts of mutations for each replication timing,... |
no.dCG.type | Get mutation type (1-4) of non-CpG mutations |
number | Convert chromosome names (character) to numeric |
OV.maf | TCGA Ovarian MAF (Mutation Annotation Format) file |
preprocess.BM | Pull out sequences, CpG dinucleotide positions, and base... |
prior | Prior probabilities that each gene is a passenger |
shuffle.muts | Simulate new dataset |
sift.col | Retrieve the column from SIFT oject correspoinding to mutated... |
sift.colA | Retrieve the column from SIFT oject correspoinding to mutated... |
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