miRNAEnrich-package: Enrichment of miRNA
In komalsrathi/miRNAEnrich: Enrichment of miRNA

Description Details Author(s) Examples

In a given microarray experiment, this package computes a fisher-based enrichment of miRNA(s) depending on the enrichment of its target genes in the gene-set of interest (upregulation/downregulation) compared to background-set (invariably the <e2><80><9c>Expressed Genes<e2><80><9d>). It utilizes the TargetScan and microRNA datatbases for miRNA-target relationship.

Package:	miRNAEnrich
Type:	Package
Version:	1.0
Date:	2015-03-10
License:	GPL-3

Run the function mirna.enrich as given in the example.

Komal Rathi Maintainer: Komal Rathi <komalr@mail.med.upenn.edu>

foreground <- background[which(background$fc < 0 & background$adj.P.Val<0.05),] #downregulated genes
res.microrna <- mirna.enrich(mir.db = 'microRNA', 
                             org = 'mmu', 
                             fg = foreground, 
                             bg = background, 
                             col = 'Symbol',
                             plot = TRUE,
                             cutoff = -0.1)