miRNAEnrich-package: Enrichment of miRNA

Description Details Author(s) Examples

Description

In a given microarray experiment, this package computes a fisher-based enrichment of miRNA(s) depending on the enrichment of its target genes in the gene-set of interest (upregulation/downregulation) compared to background-set (invariably the <e2><80><9c>Expressed Genes<e2><80><9d>). It utilizes the TargetScan and microRNA datatbases for miRNA-target relationship.

Details

Package: miRNAEnrich
Type: Package
Version: 1.0
Date: 2015-03-10
License: GPL-3

Run the function mirna.enrich as given in the example.

Author(s)

Komal Rathi Maintainer: Komal Rathi <komalr@mail.med.upenn.edu>

Examples

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foreground <- background[which(background$fc < 0 & background$adj.P.Val<0.05),] #downregulated genes
res.microrna <- mirna.enrich(mir.db = 'microRNA', 
                             org = 'mmu', 
                             fg = foreground, 
                             bg = background, 
                             col = 'Symbol',
                             plot = TRUE,
                             cutoff = -0.1)

komalsrathi/miRNAEnrich documentation built on May 20, 2019, 12:55 p.m.