expected_vaf: Estimate somatic variant allele fraction (VAF)
In kpjonsson/kpjmisc: Miscellanous Functions
expected_vaf_germline R Documentation
Estimate somatic variant allele fraction (VAF)
Description
Given copy-number and purity estimates, calculates the two expected alllele fractions of a mutation in a tumor.
Use expected_vaf_germline for germline mutations and expected_vaf_somatic for somatic mutations
Usage
expected_vaf_germline(purity, mcn, lcn)
expected_vaf_somatic(purity, mcn, lcn)
Arguments
purity
Sample purity.
mcn
Integer copy-number of major allele.
lcn
Integer copy-number of minor (lesser) allele.
Value
Object containing expected VAFs if the tumor is on the major (mcn) or minor allele (lcn), respectively.
kpjonsson/kpjmisc documentation built on Jan. 14, 2024, 2:38 a.m.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
| expected_vaf_germline | R Documentation |
Estimate somatic variant allele fraction (VAF)
Description
Given copy-number and purity estimates, calculates the two expected alllele fractions of a mutation in a tumor.
Use expected_vaf_germline for germline mutations and expected_vaf_somatic for somatic mutations
Usage
expected_vaf_germline(purity, mcn, lcn)
expected_vaf_somatic(purity, mcn, lcn)
Arguments
purity |
Sample purity. |
mcn |
Integer copy-number of major allele. |
lcn |
Integer copy-number of minor (lesser) allele. |
Value
Object containing expected VAFs if the tumor is on the major (mcn) or minor allele (lcn), respectively.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Embedding an R snippet on your website
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.