chocellcycle: Cho Yeast Cell Cycle Dataset

In laderast/Consense: Consense: a package for evaluating multiple clusterings

Description

A small subset of data derived from the Cho yeast cell cycle dataset by Yeung. The Cho dataset consists of 17 time points sampled every 10 minutes from yeast cells undergoing mitotic division. The yeast cells were synchronized to start in the late G1 phase by raising their temperature to 37ºC, which halted them in the late G1 phase. Shifting their temperature to 25ºC reinstated the cell cycle.

The 17 time points roughly correspond to two full cell cycles. The Cho dataset was part of Eisen’s original dataset for his paper showing the success of clustering. Therefore, we would expect that the clustering methods should pick up relatively similar clustering patterns.

This data has been subsetted and normalized using processes described in http://faculty.washington.edu/kayee/cluster/README_cellcycle.txt.

Usage

data(chocellcycle)

Format

A matrix of 384 genes (rows) and 17 time points (columns).

Source

http://faculty.washington.edu/kayee/cluster/

References

Yeung, K.Y., D.R. Haynor, and W.L. Ruzzo, Validating clustering for gene expression data. Bioinformatics, 2001. 17:309-18.

Cho, R.J., et al., A genome-wide transcriptional analysis of the mitotic cell cycle. Mol Cell, 1998. 2:65-73

laderast/Consense documentation built on May 20, 2019, 7:32 p.m.