dimsumms_errormodel_fit: dimsumms_errormodel_fit

In lehner-lab/dimsumms: Analysis scripts to reproduce the figures and results from DiMSum manuscript

Description

estimate multiplicative input/output and additive error terms from DMS dataset

Usage

dimsumms_errormodel_fit(DT, reps, Ncores = 1, Nbootstraps = 100,
  maxN = 10000, max_tries_per_fit = 20, lower_bound_add = 10^-4,
  Fcorr = c())

Arguments

DT	DMS dataset data.table
reps	replicates for which the error model parameters should be estimated
Ncores	how many cores to use for parallelization
Nbootstraps	# bootstraps for error model calculation
maxN	how many variants are used per bootstrap
max_tries_per_fit	how many restarts of the fitting routine in case nls doesn't yield results
lower_bound_add	lower limited for additive error terms
Fcorr	fitness normalization parameters

Value

Nothing

lehner-lab/dimsumms documentation built on June 23, 2020, 5:48 p.m.