find_differential_genes: find_differential_genes Compares to screens and finds genes...
In magStra/BSure: What the Package Does (One Line, Title Case)
View source: R/post_processing_functions.R
Description
find_differential_genes
Compares to screens and finds genes that are essential of type I or II in the first screen (controlling for FDR=0.001),
but not in the second (controlling for both FNR=FNR_II and FDR=FDR_II, to ensure low rate of false positives of differential essentiality)
This function may only be used if the second screen has sufficient power to detect essential genes compared to the first screen.
If this balance of power is lacking, calling the function will results in an error.
Usage
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find_differential_genes(
extracted_output_1,
extracted_output_2,
FDR_II = 0.05,
FNR_II = 0.1,
FNR_I = 0.05
)
Value
genes that are essential of type II in the first screen (controlling for FDR),
but not in the second (controlling for FNR)
magStra/BSure documentation built on April 27, 2021, 3:30 a.m.
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View source: R/post_processing_functions.R
Description
find_differential_genes Compares to screens and finds genes that are essential of type I or II in the first screen (controlling for FDR=0.001), but not in the second (controlling for both FNR=FNR_II and FDR=FDR_II, to ensure low rate of false positives of differential essentiality) This function may only be used if the second screen has sufficient power to detect essential genes compared to the first screen. If this balance of power is lacking, calling the function will results in an error.
Usage
1 2 3 4 5 6 7 | find_differential_genes(
extracted_output_1,
extracted_output_2,
FDR_II = 0.05,
FNR_II = 0.1,
FNR_I = 0.05
)
|
Value
genes that are essential of type II in the first screen (controlling for FDR), but not in the second (controlling for FNR)
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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