Description Usage Arguments Value Author(s)
View source: R/core_functions.R
fit_bivariate_nv2
1 2 3 4 5 6 7 | fit_bivariate_nv2(
mean_essential,
mean_NE,
sd_essential,
sd_NE,
plot_file_name = NA
)
|
mean_essential |
vector of mean log-fold changes for all gRNAs targeting core essential genes, where the mean is taken across replicates or cell lines and replicates, if there are several cell lines |
mean_NE |
vector of mean log-fold changes for all gRNAs targeting listed nonessential genes |
sd_essential |
standard deviation of log-fold changes for all gRNAs targeting core essential genes |
sd_NE |
standard deviation of log-fold changes for all gRNAs targeting listed nonessential genes |
plot_file |
name (without extension) of the file with the plot of the data and prior distribution |
parameters of bivariate normal prior distribution for mean and standard deviation of gene essentiality
Magdalena Strauss
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