mrtm1_tstar: Tstar Finder: MRTM1

In mathesong/kinfitr: Kinetic Modelling of PET Time Activity Curves

Tstar Finder: MRTM1

Description

Function to identify where t* is for MRTM1. Remember that this is unnecessary if the kinetics in the target tissue can be described by a one tissue compartment model (like SRTM).

Usage

mrtm1_tstar(
  t_tac,
  reftac,
  lowroi,
  medroi,
  highroi,
  filename = NULL,
  frameStartEnd = NULL,
  gridbreaks = 2
)

Arguments

t_tac	Numeric vector of times for each frame in minutes. We use the time halfway through the frame as well as a zero. If a time zero frame is not included, it will be added.
reftac	Numeric vector of radioactivity concentrations in the reference tissue for each frame.
lowroi	Numeric vector of radioactivity concentrations in a target tissue for each frame. This should be from a ROI with low binding.
medroi	Numeric vector of radioactivity concentrations in a target tissue for each frame. This should be from a ROI with medium binding.
highroi	Numeric vector of radioactivity concentrations in a target tissue for each frame. This should be from a ROI with high binding.
filename	The name of the output image: filename_mrtm1.jpeg
frameStartEnd	Optional: This allows one to specify the beginning and final frame to use for modelling, e.g. c(1,20). This is to assess time stability.
gridbreaks	Optional. The size of the grid in the plots. Default: 2.

Value

Saves a jpeg of the plots as filename_mrtm1.jpeg

Author(s)

Granville J Matheson, [e-mail]

Examples

## Not run: 
mrtm1_tstar(t_tac, reftac, taclow, tacmed, tachigh, "demonstration")

## End(Not run)

mathesong/kinfitr documentation built on Jan. 15, 2024, 11:07 p.m.