srtm_v_model: Model: Simplified Reference Tissue Model with Blood Volumes

In mathesong/kinfitr: Kinetic Modelling of PET Time Activity Curves

Model: Simplified Reference Tissue Model with Blood Volumes

Description

This is the SRTM model itself by which predicted values are generated.

Usage

srtm_v_model(t_tac, reftac, bloodtac, R1, k2, bp, vBr, vBt)

Arguments

t_tac	Numeric vector of times for each frame in minutes. We use the time halfway through the frame as well as a zero.
reftac	Numeric vector of radioactivity concentrations in the reference tissue for each frame.
bloodtac	Numeric vector of radioactivity concentrations in the blood for each frame.
R1	Parameter value for R1
k2	Parameter value for k2
bp	Parameter value for bp
vBr	Parameter value for vBr
vBt	Parameter value for vBt

Value

A numeric vector of the predicted values of the TAC in the target region.

Author(s)

Granville J Matheson, [e-mail]

References

Tomasi, G., Edison, P., ... & Turkheimer, F. E. (2008). Novel reference region model reveals increased microglial and reduced vascular binding of 11C-(R)-PK11195 in patients with Alzheimer's disease. Journal of Nuclear Medicine, 49(8), 1249-1256.

Examples

## Not run: 
srtm_v_model(t_tac, reftac, R1 = 0.9, k2 = 0.1, bp = 1.5, vBr = 0.05, vBt = 0.05)

## End(Not run)

mathesong/kinfitr documentation built on Jan. 15, 2024, 11:07 p.m.