twotcm_macro_model: Model: Two Tissue Compartment Model with a Macroparameter...

View source: R/kinfitr_2tcm_macro.R

twotcm_macro_modelR Documentation

Model: Two Tissue Compartment Model with a Macroparameter Parameterisation

Description

This is the Two Tissue Compartment Model model itself by which predicted values are generated.

Usage

twotcm_macro_model(t_tac, input, K1, Vnd, BPp, k4, vB)

Arguments

t_tac

Numeric vector of times for each frame in minutes. We use the time halfway through the frame as well as a zero.

input

Data frame containing the blood, plasma, and parent fraction concentrations over time. This can be generated using the blood_interp function.

K1

Parameter value for K1

Vnd

Parameter value for Vnd

BPp

Parameter value for BPp

k4

Parameter value for k4

vB

Parameter value for vB

Value

A numeric vector of the predicted values of the TAC in the target region.

Author(s)

Granville J Matheson, mathesong@gmail.com

Examples

## Not run: 
twotcm_macro_model(t_tac, input, K1 = 0.1, Vnd = 1, BPp = 2, k4 = 0.02, vB = 0.05)

## End(Not run)


mathesong/kinfitr documentation built on Nov. 27, 2024, 1:38 a.m.