fluidPage(
theme = discotheme,
fluidRow(
column(
width = 3,
box(
title = "Options",
status = "primary",
solidHeader = FALSE,
collapsible = FALSE,
width = NULL,
radioButtons(
inputId = "corMethod",
label = "Correlation Coefficient:",
choices = c("Pearson" = "pearson", "Spearman" = "spearman"),
selected = "pearson"
),
radioButtons(
inputId = "whatToCut",
label = "Set Outlier Threshold By:",
c("Correlation Value" = "value",
"Standard Deviation" = "sd"),
"sd"
),
# Slider to set correlation cutoff
conditionalPanel(
"input.whatToCut == 'value'",
sliderInput("corValue", "Outlier Threshold By Value:",
value = 0, min = 0, max = 5, step = 0.001
)
),
# Slider to set correlation cutoff
conditionalPanel(
"input.whatToCut != 'value'",
sliderInput("corSD",
"Outlier Threshold By Standard Deviation:",
value = 0, min = 0, max = 5, step = 0.1,
post = HTML("σ")
)
),
# Correlation summary text output
htmlOutput("corSummary"), br(),
downloadButton("corMatrixCSV", "CSV"),
hr(),
p(class="text-muted","Results for this section were generated
using DiscoRhythm's ",tags$code("discoInterCorOutliers()"),
" R function.")
)
),
column(
width = 9,
tabBox(
width = NULL,
id = "corTabBox",
tabPanel(
"Outlier Detection",
fluidRow(
column(10),
column(
2,
downloadButton("dlInterCt", "pdf",
class = "pull-right")
)
),
# Correlation plot
withSpinner(plotlyOutput("plotInterCTCor",
height = "600px")),
tags$hr(),
p(
class = "text-muted",
"Pairwise correlations are evaluated by the
chosen method (Pearson or Spearman) and average
correlation computed for each sample as an indication
of sample similarity. Samples sufficiently dissimilar
from all other samples will be marked as outliers.
Outlier cutoff is indicated by the horizontal line
and can be set by changing the
threshold slider in the Options panel. Every dot
below the threshold will be marked as a cross on the
plot and flagged as an outlier in
'Filtering Summary' tab. Data point
color is solely a visual aid."
)
),
tabPanel(
"Correlation Heatmap",
# Correlation heatmap and results in a table format
fluidRow(
column(
2,
h5("Number of Clusters:")
),
column(
4,
sliderInput("corNclust",
label = NULL,
value = 1, min = 1, max = 10, step = 1,
ticks = FALSE
)
),
column(4,
checkboxInput("outliersCorShowOutliers",
label = "Include Outliers",
value=FALSE)
),
column(
2,
downloadButton("dlCorHeatmapHTML", "html",
class = "pull-right")
)
),
withSpinner(plotlyOutput("plotCorrelationHeatmap",
height = "800px")),
tags$hr(),
p(
class = "text-muted",
"Heatmap of the pairwise correlations between samples.
Samples are clustered by complete-linkage
and correlation values are indicated by color.
Outliers are excluded in the heatmap by default and may
be included using the check box."
)
)
)
)
)
)
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