est_zscore: estimate Z score at a single SNP
In mdfortune/simGWAS: Simulating the expected output from a GWAS with a given causal model

Estimates the expected Z Score for a single SNP

1	est_zscore(N0, N1, Ufactor, powerfactor, freq, GenoProbXW)

`N0`	The number of Y=0
`N1`	The number of Y=1
`Ufactor`	The constant factor used to compute the expectation of U
`powerfactor`	The constant factor used to compute the expectation of the genotype of X to some power
`freq`	Frequencies of SNP appearances (computed using snphap)
`GenoProbXW`	An object giving the probability of seeing each X,W genotype vector

Assumes the input CVs, and the relationship, gamma, between them and the trait of interest

Assumes we have already generated GenoProbXW for all X

The expected Z Score for SNP X, assuming the causal SNPs are W

Mary Fortune and Chris Wallace

mdfortune/simGWAS documentation built on May 22, 2019, 3:25 p.m.

mdfortune/simGWAS index

README.md

Note that we can't provide technical support on individual packages. You should contact the package authors for that.

Description