predict_wbcc: Predict cell-type composition from methylation values

In molepi/DNAmArray: Streamlined workflow for the quality control, normalization and bias-free analysis of Illumina methylation array data - The Leiden approach

Predict cell-type composition from methylation values

Description

Predict cell percentages based on a matrix or mvr-based model

Usage

predict_wbcc(
  pred,
  data,
  covar,
  transformation = function(x) x,
  ncomp = NULL,
  impute = TRUE,
  ...
)

Arguments

pred	A matrix or mvr predictor, trained using train_wbcc
data	Matrix of DNA methylation beta values
covar	Matrix of covariates to correct for (must match those in predictor)
transformation	Transformation to apply to predicted values (default: no transformation)
ncomp	Optimal number of components
impute	Whether to impute missing values (default: TRUE)
...	Additional parameters for plsr see ?plsr

Value

Predicted cell percentages

Author(s)

mvaniterson, lsinke

molepi/DNAmArray documentation built on Aug. 24, 2022, 1:42 p.m.