sake: Single-cell RNA-Seq Analysis and Klustering Evaluation

#' Data from Usoskin et al
#'
#' Title: 'Unbiased classification of sensory neuron types
#' by large-scale single-cell RNA sequencing'
#'
#' Abstract:
#' The primary sensory system requires the integrated function of multiple cell types,
#' although its full complexity remains unclear. We used comprehensive transcriptome
#' analysis of 622 single mouse neurons to classify them in an unbiased manner, independent
#' of any a priori knowledge of sensory subtypes. Our results reveal eleven types: three
#' distinct low-threshold mechanoreceptive neurons, two proprioceptive, and six principal
#' types of thermosensitive, itch sensitive, type C low-threshold mechanosensitive and
#' nociceptive neurons with markedly different molecular and operational properties.
#' Confirming previously anticipated major neuronal types, our results also classify and
#' provide markers for new, functionally distinct subtypes. For example, our results suggest
#' that itching during inflammatory skin diseases such as atopic dermatitis is linked to a
#' distinct itch-generating type. We demonstrate single-cell RNA-seq as an effective strategy
#' for dissecting sensory responsive cells into distinct neuronal types. The resulting
#' catalog illustrates the diversity of sensory types and the cellular complexity underlying
#' somatic sensation.
#'
#' @format A data frame with 25333 genes and 864 samples:
#' \describe{
#'   \item{price}{price, in US dollars}
#'   \item{carat}{weight of the diamond, in carats}
#'   ...
#' }
#' @source \url{http://www.nature.com/neuro/journal/v18/n1/abs/nn.3881.html}
"Usoskin"