dot-rxGenFoce: Generate FOCE without interaction

In nlmixrdevelopment/RxODE: Facilities for Simulating from ODE-Based Models

Generate FOCE without interaction

Description

Generate FOCE without interaction

Usage

.rxGenFoce(
  obj,
  predfn,
  pkpars = NULL,
  errfn = NULL,
  init = NULL,
  pred.minus.dv = TRUE,
  sum.prod = FALSE,
  optExpression = TRUE,
  promoteLinSens = TRUE,
  theta = FALSE,
  addProp = c("combined2", "combined1")
)

Arguments

obj	RxODE object
predfn	Prediction function
pkpars	Pk Pars function
errfn	Error function
init	Initialization parameters for scaling.
pred.minus.dv	Boolean stating if the FOCEi objective function is based on PRED-DV (like NONMEM). Default TRUE.
sum.prod	A boolean determining if RxODE should use more numerically stable sums/products.
optExpression	Optimize the model text for computer evaluation.
promoteLinSens	Promote solved linear compartment systems to sensitivity-based solutions.
theta	Calculate THETA derivatives instead of ETA derivatives. By default FALSE
addProp	one of "combined1" and "combined2"; These are the two forms of additive+proportional errors supported by monolix/nonmem: combined1: transform(y)=transform(f)+(a+b*f^c)*eps combined2: transform(y)=transform(f)+(a^2+b^2*f^(2c))*eps

Value

RxODE/symengine environment

Author(s)

Matthew Fidler

nlmixrdevelopment/RxODE documentation built on April 10, 2022, 5:36 a.m.