explore_biomarkers: Examination of possible relevant biomarkers in cancer dataset

In olapuentesantana/easier_manuscript: Evaluate patient immune response to ICBs through a systems approach

Description

explore_biomarkers provides an overview of the mechanistic signatures features distribution in the dataset (separating responders and non-responders if known) together with information on the feature contribution to the model building.

Usage

explore_biomarkers(
  pathways,
  immunecells,
  lrpairs,
  cytokinepairs,
  tfs,
  ccpairsgroupedscores,
  ccpairsgroupedpval,
  cancertype,
  real_patient_response,
  output_file_path
)

Arguments

pathways	numeric matrix with data
immunecells	numeric matrix with data
lrpairs	numeric matrix with data
cytokinepairs	numeric matrix with data
tfs	numeric matrix with data
ccpairsgroupedscores	numeric matrix with data
ccpairsgroupedpval	numeric matrix with data
cancertype	string character
real_patient_response	vector with two factors (NR,R)
output_file_path	string with a file name

Value

boxplot with features distribution

olapuentesantana/easier_manuscript documentation built on Sept. 22, 2021, 9:42 p.m.