calc_llh: Calculates likelihood of the genome with respect to the...

In parklab/SigMA: Signature Multivariate Analysis

Calculates likelihood of the genome with respect to the available signature probability distributions

Description

Calculates likelihood of the genome with respect to the available signature probability distributions

Usage

calc_llh(spectrum, signatures, counts = NULL, normalize = T)

Arguments

spectrum	is the mutational spectrum
signatures	is the reference signature catalog with the probability distributions
counts	is the number of cases in each cluster that is represented in the catalog. They are used as weights for each signature in the catalog
normalize	is true by default only for when it is used together with NNLS in the match_to_catalog function it is not normalized here but outside of the function

parklab/SigMA documentation built on Feb. 10, 2024, 6:59 p.m.