chipSmooth: Accessor methods for 'chipSmooth' slot in a...

chipSmoothR Documentation

Accessor methods for chipSmooth slot in a parameterOptions object.

Description

Access or Extract chipSmooth slot in a parameterOptions object.

Usage

chipSmooth(object)

Arguments

object

object is a parameterOptions object.

Details

When computing ChIP-seq like (computeChIPProfile) profile from occupancy data (see computeOccupancy), the profiles are smoothed using a window of a given size. The default value is set at 250 base pairs. If chipSmooth is set to 0 then the profile will not be smoothed. We strongly encourage to set values when building a parameterOptions object.

Value

Returns the chipSmooth slot in an parameterOptions object.

Author(s)

Patrick C.N. Martin <pcnmartin@gmail.com>

References

Zabet NR, Adryan B (2015) Estimating binding properties of transcription factors from genome-wide binding profiles. Nucleic Acids Res., 43, 84–94. Patrick C.N. Martin and Nicolae Radu Zabe (2020) Dissecting the binding mechanisms of transcription factors to DNA using a statistical thermodynamics framework. CSBJ, 18, 3590-3605.

Examples

# Building parameterOptions object
OPP <- parameterOptions()
# Accessing chipSd slot
chipSmooth(OPP)

patrickCNMartin/ChIPanalyser documentation built on Dec. 5, 2024, 9:32 a.m.