The function find the DMVs defined by Xie et al in Cell 2013. To identify each DMVs in a cell type, the genome was first divided in 1kb bins and the DNA methylation level was averaged within each bin. Then a sliding 5kb window (with 1kb step) was used to identify regions that have an averaged methylation level less than 0.15 in a 5kb window. Continuous regions resulting from this analysis were then merged to form DMVs.
A matrix contains the methylation ratios. Columns are samples and rows are sites. Each rowname is like 'chrX.NNNNN'
A dataframe shows the methylation of 5kb-1kbstep regions of each sample.
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