findDMVS: The function find the DMVs defined by Xie et al in Cell 2013....

Description Usage Arguments Value

View source: R/findDMVS.R

Description

The function find the DMVs defined by Xie et al in Cell 2013. To identify each DMVs in a cell type, the genome was first divided in 1kb bins and the DNA methylation level was averaged within each bin. Then a sliding 5kb window (with 1kb step) was used to identify regions that have an averaged methylation level less than 0.15 in a 5kb window. Continuous regions resulting from this analysis were then merged to form DMVs.

Usage

1
findDMVS(methyMatrix)

Arguments

methyMatrix:

A matrix contains the methylation ratios. Columns are samples and rows are sites. Each rowname is like 'chrX.NNNNN'

Value

A dataframe shows the methylation of 5kb-1kbstep regions of each sample.


ritianjiang/MethyAge2 documentation built on Dec. 3, 2019, 2:03 p.m.