dorothea_mm_pancancer: Mouse DoRothEA (pancancer)

dorothea_mm_pancancerR Documentation

Mouse DoRothEA (pancancer)

Description

A table reporting signed human TF-target interactions. The difference to "dorothea_mm" is that TGCA gene expression data was used instead of GTEx to infer the networks with ARACNE.This database covers in total 1096 TFs targeting 17,695 genes with 187,955 unique interactions. In addition, each TF is accompanied with an empirical confidence level that was derived from the number of supporting evidences for this TF/interaction. The range is from A (high quality) to E (low quality).

Format

A table of mouse TF-target interactions:

tf

TF identifier as MGI symbols

confidence

summary confidence score classifying regulons based on their quality

target

target identifier as MGI symbols

mor

mode of regulation indicating the effect of a TF on the target

Source

https://www.ncbi.nlm.nih.gov/pubmed/31525460


saezlab/dorothea documentation built on Feb. 24, 2024, 8:12 p.m.