Sphere of Influence assesses if a candidate gene i meets the first criterion by testing if gene i is more strongly correlated with its network neighbors than with a random set of genes
1 2 | Resample.SI(gene.id, distance.matrix, cor.matrix, diameter,
num.Sphere.resamples = 1000, genes.assayedETnetwork)
|
gene.id |
The name of the gene to which GeneSurrounder is applied |
distance.matrix |
A matrix of the distances on the global network |
cor.matrix |
A matrix of correlations between the expression of the genes |
diameter |
The diameter of the global network |
num.Sphere.resamples |
defaults to 1000. The number of resamples when running the Sphere of Influence Procedure |
genes.assayedETnetwork |
The names of the genes that are assayed and on the network |
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