TopGenesMRMR: Selects the top ranked (differentially expressed) genes...

Description Usage Arguments Details Value Author(s) Examples

View source: R/TopGenesMRMR.R

Description

Function 'TopGenesMRMR' returns the list of top ranked genes selected through Maximum Relevance and Minimum Redundancy (MRMR) method.

Usage

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TopGenesMRMR(x, y, n)

Arguments

x

Nxp data frame of gene expression values, where, N represents number of genes and p represents samples/time points generated in a case vs. control gene expression study.

y

px1 numeric vector with entries 1 and -1 representing sample/subject labels, where 1 and -1 represents the labels of subjects/ samples for case and control condition respectively.

n

Numeric constant (< N) representing the number of top ranked genes to be selected from the gene expression data.

Details

Selects the top ranked (differentially expressed) genes through MRMR method.

Value

A list of differentially expressed specified number of genes through MRMR method.

Author(s)

Samarendra Das <samarendra4849 at gmail.com>

Examples

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x=as.data.frame(matrix(runif(1000), 50))
row.names(x) = paste("Gene", 1:50)
colnames(x) = paste("Samp", 1:20)
y=as.numeric(c(rep(1, 10), rep(-1, 10)))
TopGenesMRMR(x, y, n=5)

sam-uofl/BSM documentation built on Sept. 6, 2020, 12:09 a.m.