extractAUCXtab: FOR INTERNAL USE ONLY: Extract PK data from a generic AUC...

In shirewoman2/Consultancy: Standardized tools for using R within the Simcyp Consultancy Team

FOR INTERNAL USE ONLY: Extract PK data from a generic AUC tab, e.g., NOT one formatted like the "AUC" tab from Simcyp V21 and earlier

Description

FOR INTERNAL USE ONLY: Extract PK data from a generic AUC tab, e.g., NOT one formatted like the "AUC" tab from Simcyp V21 and earlier

Usage

extractAUCXtab(
  PKparameters,
  PKparameters_orig,
  compoundToExtract = "substrate",
  sim_data_file,
  Sheet,
  PKset,
  UserSpecified,
  Deets,
  DataCheck,
  includeTrialInfo
)

Arguments

PKparameters	parameters to extract; character vector only (a set of parameters like in extractPK is not acceptable here)
PKparameters_orig	original PK parameters from extractPK function
compoundToExtract	For which compound do you want to extract PK data? Options are: "substrate" (default), "primary metabolite 1", "primary metabolite 2", "secondary metabolite", "inhibitor 1" – this can be an inducer, inhibitor, activator, or suppresesor, but it's labeled as "Inhibitor 1" in the simulator, "inhibitor 2" for the 2nd inhibitor listed in the simulation, "inhibitor 1 metabolite" for the primary metabolite of inhibitor 1
sim_data_file	simulator output Excel file to read
Sheet	sheet to read from the Excel file
PKset	which set of PK parameters to use. Options: AUC0, AUClast, AUCX
UserSpecified	TRUE or FALSE for whether this was a user-specified sheet, in which case we don't know which dose it is
Deets	output from running extractExpDetails on the provided sim_data_file and setting Deets <- existing_exp_details$MainDetails
DataCheck	DataCheck data.frame
includeTrialInfo	TRUE or FALSE

Value

a list for use with the extractPK function

Examples

# none

shirewoman2/Consultancy documentation built on Feb. 18, 2025, 10 p.m.