extract_fu: Extract fu,plasma values that change with time from a...

In shirewoman2/Consultancy: Standardized tools for using R within the Simcyp Consultancy Team

Extract fu,plasma values that change with time from a Simulator output Excel file. UNDER CONSTRUCTION!

Description

extract_fu extracts the time-dependent fraction unbound in plasma from a simulator output Excel file. A tab named something like "fu Profile (Sub)" must be present. This currently only extracts data for the substrate, but if you have an example with a different compound, please talk to Laura Shireman. UNDER CONSTRUCTION!

Usage

extract_fu(
  sim_data_files,
  returnAggregateOrIndiv = "both",
  existing_exp_details = NA
)

Arguments

sim_data_files	the Simcyp Simulator Excel results files containing the simulated time-dependent fu data, in quotes
returnAggregateOrIndiv	Return aggregate and/or individual simulated fu data? Options are "individual", "aggregate", or "both" (default). Aggregated data are not calculated here but are pulled from the simulator output rows labeled as "mean".
existing_exp_details	If you have already run extractExpDetails_mult or extractExpDetails to get all the details from the "Input Sheet" (e.g., when you ran extractExpDetails you said exp_details = "Input Sheet" or exp_details = "all"), you can save some processing time by supplying that object here, unquoted. If left as NA, this function will run extractExpDetails behind the scenes to figure out some information about your experimental set up.

Value

a data.frame

Examples

# None yet

shirewoman2/Consultancy documentation built on Feb. 18, 2025, 10 p.m.