RnaSeqSampleSize package provides a sample size calculation method based on negative binomial model and the exact test for assessing differential expression analysis of RNA-seq data. It controls FDR for multiple testing and utilizes the average read count and dispersion distributions from real data to estimate a more reliable sample size. It is also equipped with several unique features, including estimation for interested genes or pathway, power curve visualization, and parameter optimization.
|Bioconductor views||DifferentialExpression ExperimentalDesign GeneExpression ImmunoOncology RNASeq Sequencing|
|License||GPL (>= 2)|
|Package repository||View on GitHub|
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