sample_size: sample_size

In slzhao/RnaSeqSampleSize: RnaSeqSampleSize

sample_size

Description

A function to estitamete the sample size for differential expression analysis of RNA-seq data.

Usage

sample_size(
  power = 0.8,
  m = 20000,
  m1 = 200,
  f = 0.1,
  k = 1,
  w = 1,
  rho = 2,
  lambda0 = 5,
  phi0 = 1,
  showMessage = FALSE,
  storeProcess = FALSE
)

Arguments

power	Power to detect prognostic genes.
m	Total number of genes for testing.
m1	Expected number of prognostic genes.
f	FDR level
k	Ratio of sample size between two groups (Treatment/Control).
w	Ratio of normalization factors between two groups.
rho	minimum fold changes for prognostic genes between two groups (Treatment/Control).
lambda0	Average read counts for prognostic genes.
phi0	Dispersion for prognostic genes.
showMessage	Logical. Display the message in the estimation process.
storeProcess	Logical. Store the power and n in sample size or power estimation process.

Details

A function to estitamete the sample size for differential expression analysis of RNA-seq data.

Value

Estimate sample size or a list including parameters and sample size in the process.

Examples

power<-0.8;rho<-2;lambda0<-5;phi0<-0.5;f<-0.01
sample_size(power=power, f=f,rho=rho, lambda0=lambda0, phi0=phi0)

slzhao/RnaSeqSampleSize documentation built on March 24, 2022, 2:21 a.m.