model {
# Define likelihood model for data:
for (p in 1:N_patients)
{
for(a in 1:antibiotic_classes)
{
response[h_GUID[p],a] ~ dbern(ahwtw.prob[a,
sample_month[h_sample_GUID[p]],
age_group[h_sample_GUID[p]],
gender[h_sample_GUID[p]],
hospital[ward[h_sample_GUID[p]]],
ward_type[ward[h_sample_GUID[p]]],
ward[h_sample_GUID[p]]])
}
}
for (gp in 1:N_gp)
{
for(a in 1:antibiotic_classes)
{
response[gp_GUID[gp],a] ~ dbern(asmagg.gpw.prob[
a,
sample_month[gp_sample_GUID[gp]],
age_group[gp_sample_GUID[gp]],
gender[gp_sample_GUID[gp]]])
}
}
for (v in 1:N_volunteers)
{
for(a in 1:antibiotic_classes)
{
response[v_GUID[v],a] ~ dbern(asmagg.vw.prob[
a,
sample_month[v_sample_GUID[v]],
age_group[v_sample_GUID[v]],
gender[v_sample_GUID[v]]])
}
}
for (o in 1:N_outpatients)
{
for(a in 1:antibiotic_classes)
{
response[o_GUID[o],a] ~ dbern(asmagg.ow.prob[
a,
sample_month[o_sample_GUID[o]],
age_group[o_sample_GUID[o]],
gender[o_sample_GUID[o]]])
}
}
# ------------------------
# Define the priors:
for(a in 1:antibiotic_classes)
{
antibiotic.class.effect[a] ~ dnorm(intercept, tau.class)
logit(a.prob[a]) <- antibiotic.class.effect[a]
}
for(m in 1:N_sample_month)
{
samplemonth.effect[m] ~ dnorm(0, tau.samplemonth)
}
for (g in 1:N_age_group)
{
agegroup.effect[g] ~ dnorm(0, tau.agegroup)
logit(agegroup.prob[g]) <- agegroup.effect[g]
}
gender.effect[female] ~ dnorm(0, 0.001)
gender.effect[male] <- -gender.effect[female]
for (h in 1:N_hosp)
{
h.effect[h] ~ dnorm(0, tau.hosp)
logit(h.prob[h]) <- h.effect[h]
}
# equivalent to h.effect
nh.effect ~ dnorm(0, tau.hosp)
logit(nh.prob) <- nh.effect
for (wt in hosp_wardtypes)
{
wt.effect[wt] ~ dnorm(0, tau.wt)
}
# equivalent to wt.effect
gp.effect ~ dnorm(nh.effect, tau.wt)
v.effect ~ dnorm(nh.effect, tau.wt)
o.effect ~ dnorm(nh.effect, tau.wt)
for (w in hosp_wards)
{
ward.effect[w] ~ dnorm(0, tau.ward)
}
# equivalent to wtw.effect
gpw.effect ~ dnorm(gp.effect, tau.ward)
vw.effect ~ dnorm(v.effect, tau.ward)
ow.effect ~ dnorm(o.effect, tau.ward)
# ------------------------
for(a in 1:antibiotic_classes)
{
for(m in 1:N_sample_month)
{
for (r in 1:N_age_group)
{
for (g in genders)
{
asmagg.effect[a,m,r,g] <- antibiotic.class.effect[a] +
samplemonth.effect[m] + agegroup.effect[r] + gender.effect[g]
for (h in 1:N_hosp)
{
for (wt in hosp_wardtypes)
{
for (w in hosp_wards)
{
logit(ahwtw.prob[a,m,r,g,h,wt,w]) <- asmagg.effect[a,m,r,g] +
h.effect[h] + wt.effect[wt] + ward.effect[w]
}
}
}
# equivalent to awt.prob
logit(asmagg.gpw.prob[a,m,r,g]) <- asmagg.effect[a,m,r,g] + gpw.effect
logit(asmagg.vw.prob[a,m,r,g]) <- asmagg.effect[a,m,r,g] + vw.effect
logit(asmagg.ow.prob[a,m,r,g]) <- asmagg.effect[a,m,r,g] + ow.effect
}
}
}
}
# Prior value for intercept (log-odds of the average resistance in all samples)
intercept ~ dnorm(0, 0.001)
# Prior values for precision
tau.class ~ dgamma(0.001, 0.001)
tau.samplemonth ~ dgamma(0.001, 0.001)
tau.agegroup ~ dgamma(0.001, 0.001)
tau.hosp ~ dgamma(0.001, 0.001)
tau.wt ~ dgamma(0.001, 0.001)
tau.ward ~ dgamma(0.001, 0.001)
# Convert precisions to sd
sd.class <- sqrt(1/tau.class)
sd.samplemonth <- sqrt(1/tau.samplemonth)
sd.agegroup <- sqrt(1/tau.agegroup)
sd.hosp <- sqrt(1/tau.hosp)
sd.wt <- sqrt(1/tau.wt)
sd.ward <- sqrt(1/tau.ward)
#monitor# full.pd, dic, deviance, a.prob, intercept, sd.class, sd.samplemonth, sd.agegroup, sd.hosp, sd.wt, sd.ward
}
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