malaria: Malaria Transmission and Parasites

In speegled/fosdata: Data for use with the book "Probability, Statistics, and Data: A Fresh Approach Using R", by Darrin Speegle and Bryan Clair

Malaria Transmission and Parasites

Description

Mice were bit 10 times by mosquitoes, and the number of salivary gland sporozoites detected in the mosquitoes was measured. The mice were then observed to determine whether they got malaria. Some of the mice were given a malarial antibody pre-mosquito bite.

Usage

malaria

Format

A tibble with 180 observations of 3 variables.

sporozoite

The total number of sporozoites detected from the 10 bites.

malaria

1 = yes malaria detected, 0 = no malaria detected

antibody

yes/no did the mouse receive an antibody treatment pre-mosquito bites

Details

From the authors: "Over a century since Ronald Ross discovered that malaria is caused by the bite of an infectious mosquito it is still unclear how the number of parasites injected influences disease transmission. Currently it is assumed that all mosquitoes with salivary gland sporozoites are equally infectious irrespective of the number of parasites they harbour, though this has never been rigorously tested."

Source

Churcher TS, Sinden RE, Edwards NJ, Poulton ID, Rampling TW, Brock PM, et al. (2017) Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts. PLoS Pathog 13(1): e1006108. https://doi.org/10.1371/journal.ppat.1006108

speegled/fosdata documentation built on Feb. 8, 2025, 8:17 a.m.