Description Usage Arguments Value Examples
Calculate statistical power in a de novo burden analysis.
1 | getDeNovoBurdenPower(R, N, r, q, f, p_thres_denovo_burden)
|
R |
Relative Risk (numeric). |
N |
Sample Size (integer). |
r |
Case:Control ratio (numeric). |
q |
Total number of variants within selected regions per control individual (numeric). |
f |
Percent of variants within selected regions that mediate disease risk (numeric). |
p_thres_denovo_burden |
p-value threshold after correction for multiple comparisons (numeric, 0-1). |
The statistical power in a de novo cohort.
1 | getDeNovoBurdenPower(25, 5000, 1, 0.0249, 0.2, 5e-5)
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