getSingleVarLocusPower: Calculates the power of rare variant locus discovery in cases...

In stephansanders/wgsPowerTest: Whole Genome Sequencing Power Calculations

Description

Calculates the power of rare variant locus discovery in cases and controls.

Usage

getSingleVarLocusPower(f, AF, R, K, N, r, p_thres_cc_locus_single)

Arguments

f	Proportion of variants that mediate risk (numeric, 0-1).
AF	Allele frequency (numeric, 0-1).
R	Relative Risk (numeric).
K	Prevalence of the disorder (numeric, 0-1).
N	Sample Size (integer).
r	Case:Control ratio (numeric).
p_thres_cc_locus_single	p-value threshold after correction for multiple comparisons (numeric, 0-1).

Value

The statistical power (numeric, 0-1).

Examples

getSingleVarLocusPower(0.2, 1e-4, 2.5, 0.01, 20000, 1, 1.666667e-11)

stephansanders/wgsPowerTest documentation built on May 4, 2019, 1:23 p.m.