getDeNovoLocusPowerParametric: Calculates the power of de novo mutation burden in de novo...

In stephansanders/wgsPowerTest: Whole Genome Sequencing Power Calculations

Description

Calculates the power of de novo mutation burden in de novo cohorts.

Usage

getDeNovoLocusPowerParametric(R, q, f, N, r, p_thres_denovo_burden)

Arguments

R	Relative Risk (numeric).
q	Total number of de novo mutations within selected regions per control individual (numeric).
f	Proportion of de novo mutations that mediate risk (numeric, 0-1).
N	Sample Size (integer).
r	Case:Control ratio (numeric).
p_thres_denovo_locus	p-value threshold after correction for multiple comparisons (numeric, 0-1).

Value

The statistical power (numeric, 0-1).

Examples

getDeNovoLocusPowerParametric(25, 0.0249, 0.2, 5000, 1, 5e-05)

stephansanders/wgsPowerTest documentation built on May 4, 2019, 1:23 p.m.