AddNoise: Exposures and spectra with Poisson or negative binomial noise...

In steverozen/SynSigGen: Create Catalogs of Synthetic Mutational Spectra

Exposures and spectra with Poisson or negative binomial noise in exposures.

Description

Exposures and spectra with Poisson or negative binomial noise in exposures.

Usage

AddNoise(input.exposure, signatures, n.binom.size = 100)

Arguments

input.exposure	The exposures to which to add noise; a numeric matrix or data frame in which the rows are signatures and the columns are samples. Each cell indicates the number of mutations due to a particular signature in a particular sample.
signatures	The signatures in the exposure; the column names of signatures have to include all row names in input.exposure; can be an ICAMS catalog or a numerical matrix or data frame.
n.binom.size	If non NULL, use negative binomial noise with this size parameter; see NegBinomial. If NULL, use Poisson noise.

Value

A list with the elements

expsoures

The numbers of mutations due to each signature after adding noise

spectra

The spectra based on the noisy signature exposures.

steverozen/SynSigGen documentation built on April 1, 2022, 8:54 p.m.