Create1CatRandomExpRandomSigs: Create a catalog of "random" synthetic spectra for 96-channel...

In steverozen/SynSigGen: Create Catalogs of Synthetic Mutational Spectra

Create a catalog of "random" synthetic spectra for 96-channel mutation types.

Description

Create a catalog of "random" synthetic spectra for 96-channel mutation types.

Usage

Create1CatRandomExpRandomSigs(
  num.syn.tumors,
  total.num.sigs,
  mut.mean,
  mut.sd,
  mean.num.sigs.per.tumor,
  sd.num.sigs.per.tumor,
  dir.name,
  overwrite = FALSE,
  verbose = TRUE
)

Arguments

num.syn.tumors	Total number of synthetic tumors to create.
total.num.sigs	Total number of signatures in the universe.
mut.mean	Mean of the log10 of the number of mutations due to each signature.
mut.sd	Standard deviation of the log10 of the number of mutations due to each signature.
mean.num.sigs.per.tumor	Mean number of signatures contributing to each tumor.
sd.num.sigs.per.tumor	Standard deviation the number of signatures in each tumor.
dir.name	A string indicating the name of the 96-channel subdirectory; probably one of "sa.sa.COMPOSITE" or "sp.sa.COMPOSITE".
overwrite	If TRUE overwrite existing directories / files.
sig.name.prefix	String to put in front of an integer (as string) to form an identifier for a synthetic signature.
sample.name.prefix	String to put in front of an integer (as string) to form an identifier for a synthetic sample (tumor).
COMPOSITE.features	Character vector containing rownames for a COMPOSITE signature or catalog.

steverozen/SynSigGen documentation built on April 1, 2022, 8:54 p.m.