struckma/synergyfinder: Calculate and Visualize Synergy Scores for Drug Combinations

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix. This fork has an updated PlotDoseResponse function, with adaptions from hly89, a work-around for knitr compatibility (quite ugly but working) by Stephan Struckmann and a bug fix regarding swapped dimensions for the heatmap plot also by Stephan Struckmann.

Getting started

Package details

AuthorLiye He <>, Jing Tang <>, Stephan Struckmann <>
Bioconductor views Software Statistical Method
MaintainerLiye He <>
LicenseArtistic License 2.0
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
struckma/synergyfinder documentation built on May 17, 2019, 11:18 p.m.