NEWS.md

In tanaylab/repguide: Design CRISPR guide RNAs against DNA repetitive sequences

Repguide 0.0.1.5

Bug Fixes

• Now supports dplyr 1.0.0

Repguide 0.0.1.4

Perfomance

• Speed enhancement for addGuides function

Bug Fixes

• Throws guides with identical sequence up to PAM before alignment

Repguide 0.0.1.3

Bug Fixes

• Export bug fix resolving mismatch between number of guides in file name and internal number of sequences

Repguide 0.0.1.2

Bug Fixes

• Prevents greedy search from adding the same guide multiple times

Features

• Parameter five_prime_seq added to addGuides function to restrict analyses to guides starting with certain nucleotide (e.g. G for transcription from U6 promoter)

Repguide 0.0.1.1

Bug Fixes

• Export crash fix
• Added prefix to unique_id column to distinguish TE and genomic bin ids.
• Fixed plotTargets panel f arrangement to match that of panels d and e.

Repguide 0.0.1.0

• This is the first release of Repguide

tanaylab/repguide documentation built on June 29, 2020, 9:29 a.m.