insulin: Insulin assay.

insulinR Documentation

Insulin assay.

Description

The data are from a study designed to determine if the effect of two insulins is additive or synergistic.

Usage

insulin

Format

A data frame with 56 observations and four variables:

y:

conversion of (3-3H) glucose to toluene-extractable lipids in isolated rat fat cells

insulin1:

dose of standard insulin (pmol/liter)

insulin2:

dose of A1-B29 suberoyl insulin (pmol/liter)

ratio:

ratio of standard insulin to A1-B29 suberoyl insulin

Details

These data were featured in Darby and Ellis (1976) and also McCullagh and Nelder (1989). In particular see the latter for a discussion of a nonlinear gamma regression model for these data.

Source

Darby, S. C. & Ellis, M. J. (1976). A test of synergism between two drugs. Applied Statistics, 25, 296-299.

McCullagh, P. & Nelder, J. A. (1989). Generalized linear models (2nd Edition). Boca Raton: Chapman & Hall/CRC.


trobinj/trtools documentation built on Jan. 28, 2024, 3:20 a.m.