Description Usage Arguments Value
fit the dalla Man version of the Bergman minimal model (piecewise linear form for rate of appearance of glucose)
1 2 3 4 5 | fitOneMinMod(insulin, glucose, bodyweight, times, nlsmaxit = 100,
nlstol = 0.1, fullNLScontrol = NULL, nlstrace = FALSE, Sg = 0.028,
V = 1.34, D = 75000, FA = 0.87, DC = 0.017, p2 = 0.012,
nlsinit = list(a1 = 4, a2 = 4, a3 = 4, SI = 1e-04), trajTimes = 0:120,
inputID = "")
|
insulin |
a numeric vector of insulin values recorded at times in |
glucose |
a numeric vector of glucose concentrations, same length as |
bodyweight |
a numeric scalar |
times |
times in minutes |
nlsmaxit |
maximum number of iterations for NLS |
nlstol |
tolerance for convergence of NLS |
fullNLScontrol |
an optional list of control parameters for NLS |
nlstrace |
logical requesting retention of trace |
Sg |
fractional glucose effectiveness (default 0.028 min^-1) |
V |
volume of distribution (default 1.34 dl/kg) |
D |
ingested glucose dose in mg (default 75000) |
FA |
fraction of glucose dose that is absorbed, default = 0.87, dimensionless |
DC |
decay constant for model for rate of appearance of glucuse, default 0.017 |
p2 |
rate constant of the remote insulin compartment from which insulin action emanates, default value 0.012 min^-1 |
nlsinit |
initial values for unknown parameters a1, a2, a3 (coefficients of piecewise linear model for rate of appearance of glucose) and SI (insulin sensitivity) |
trajTimes |
a vector of times at which glucose and insulin trajectories should be estimated |
inputID |
a string that may be used for rendering an ID tag |
a list with elements fit
for the NLS fit, soln
for the lsoda based solution to the differential equation model, pwlinRa
for the piecewise-linear estimate of Ra (rate of appearance of glucose), input
for a sublist with information about the input data, and sessInf
for the sessionInfo metadata
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